Cytopathogenicity in Tissue Cultures by a Tumor Virus from Mice

Bernice E. Eddy, Sarah E. Stewart, William Berkeley

Experimental Biology and Medicine · 1958 · 85 citations · 0 references

Concepts

Abstract

SummaryCytopathogenic changes were observed in mouse embryo cell cultures that had been inoculated with tissue culture-grown virus isolated from mouse tumor tissues. Quantitative assays of the virus, referred to as the SE polyoma virus, and serum-virus neutralization tests were correlated with the induction of tumors in hamsters.