Management of Hyperkalemia with a Cation-Exchange Resin

Abstract

IN patients with advanced renal insufficiency hyperkalemia may lead to death by its myocardial effects.1 , 2 Glucose and insulin solutions, calcium and hypertonic sodium salts, intestinal and peritoneal lavage, extracorporeal hemodialysis, hormone administration, infusion of alkali salts such as sodium bicarbonate and sodium lactate and cation-exchange resins have been used in the management of this problem.3 4 5 This report describes the use of a sulfonic polystyrene cation-exchange resin in the sodium cycle∥ for the control of hyperpotassemia in both acute and chronic renal disease.Synthetic ion-exchange resins were first made available to industry in 1935 and have since been extensively adapted to . . .