Rhodium(III)-Catalyzed C–H Olefination for the Synthesis of <i>ortho</i>-Alkenyl Phenols Using an Oxidizing Directing Group

Abstract

By using an oxidizing directing group, a mild, efficient Rh(III) catalyzed C–H olefination reaction between N-phenoxyacetamides and alkenes was developed. This reaction provided a straightforward way for the synthesis of ortho-alkenyl phenols, and the directing group is traceless in the product.