HYPERLIPOFUSCINOSIS AND SUBRETINAL FIBROSIS IN STARGARDTʼS DISEASE

Abstract

It is presumed that the abnormal material in the two first patients is lipofuscin and that this represents an exaggerated response of the diseased retinal pigment epithelium, possibly to a minor trauma. That material will eventually be replaced by subretinal fibrosis. The fundus appearance in the third patient is possibly the result of a similar process.