American Journal of Psychiatry · 1988 · 88 citations · 23 references
MedicineEndocrinologyPsychiatryAddiction PsychiatryNeuroendocrinologySubstance Use DisordersAdrenal EndocrinologyAdrenal HormonesDrug DependencePituitary Gland FunctionPituitary HormonesSubstance WithdrawalAnterior Pituitary Hormone SecretionHypothalamic HormonesHypothalamic Regulation Of ProlactinHypothalamic-pituitary-prolactin AxisPhysiological HyperprolactinemiaPituitary HypersecretionPituitary PhysiologyProlactin Secretion Regulation
Plasma luteinizing hormone (LH), prolactin, testosterone, and cortisol levels were determined in 16 patients after hospital admission for cocaine abuse, during the course of 4 weeks of hospitalization, and before discharge. Hyperprolactinemia was found at admission (mean +/- SD, 27.5 +/- 10.2 ng/ml) and persisted until discharge (mean +/- SD, 28.7 +/- 10.8 ng/ml). Plasma LH, testosterone, and cortisol levels were within normal limits. These findings suggest that persistent elevation of plasma prolactin levels after cocaine withdrawal may reflect a chronic cocaine-induced derangement in neural dopaminergic regulatory systems.
23
Harrison's Principles of Internal Medicine.
Annals of Internal Medicine · 1988 · 12.6K citations
Cocaine Receptors on Dopamine Transporters Are Related to Self-Administration of Cocaine
Mary C. Ritz, R. J. Lamb, Steven R. Goldberg et al. · Science · 1987 · 2.2K citations
Medicine, Neuroscience, Pharmacology +14