Increased 8-hydroxy-2’-deoxyguanosine in leukocyte DNA from patients with type 2 diabetes and microangiopathy

Abstract

Leukocyte oxidative DNA damage was high in patients with type 2 diabetes and microangiopathy. Presence of microangiopathy was associated with leukocyte 8-OHdG levels, duration of type 2 diabetes, albuminuria and use of ACE inhibitors/ARBs or insulin.