Associations between serum CA724 and HER2 overexpression among stage II-III resectable gastric cancer patients: an observational study

Abstract

Serum CA724 is significantly associated with the overexpression of HER2 among locally advanced gastric cancer patients. The combination of CA724, CA199, CEA and CA125 is better than serum CA724 alone in predicting HER2 overexpression. External validation and further investigation of the biological mechanisms of these associations are required.