NEUTRALIZATION OF INFECTIOUS BRONCHITIS VIRUS HUMAN SERA1

Abstract

Miller, L. T., and V. J. Yates (Univ. of Rhode Island, Kingston, R. I.). Neutralizazation of infectious bronchitis virus by human sera. Amer. J. Epid. 1968, 88: 406–409.—Infectious bronchitis virus (IBV) produces a respiratory infection in chickens. Human infections involving other viruses of chickens have been reported, but human infection with IBV has not been observed. In this study the sera of one group of individuals who were associated with poultry and a control group with limited poultry association were tested for their ability to neutralize IBV. Reactors were found only among individuals who worked closely with poultry. The greatest number of reactions were found in serum from individuals who were between the ages 30–59. The majority of these sera had only low levels of anti-IBV activity. The significance of these findings is discussed.