The Journal of the Acoustical Society of America · 2016 · 40 citations · 22 references
MedicineBiomedical EngineeringAcousticsUltrasonographyUltrasoundDiagnostic UltrasonographyTransducer TechnologyUltrasonicsUltrasound InstrumentationUltrasound PhysicsAcoustic Detection Of CavitationAcoustic ImpedanceBandwidthHydrophonesTherapeutic Ultrasound TransducersTransducersUltrasonic AcousticsUltrasonic Transducers
The output characterization of medical high intensity therapeutic ultrasonic devices poses several challenges for the hydrophones to be used for pressure measurements. For measurements at clinical levels in the focal region, extreme robustness, broad bandwidth, large dynamic range, and small receiving element size are all needed. Conventional spot-poled membrane hydrophones, in principle, meet some of these features and were used to detect large amplitude ultrasonic fields to investigate their applicability. Cavitation in water was the limiting effect causing damage to the electrodes and membrane. A new hydrophone design comprising a steel foil front protection layer has been developed, manufactured, characterized, tested, and optimized. The latest prototypes additionally incorporate a low absorption and acoustic impedance matched backing, and could be used for maximum peak rarefactional and peak compressional pressure measurements of 15 and 75 MPa, respectively, at 1.06 MHz driving frequency. Axial and lateral beam profiles were measured also for a higher driving frequency of 3.32 MHz to demonstrate the applicability for output beam characterization at the focal region at clinical levels. The experimental results were compared with results of numerical nonlinear sound field simulations and good agreement was found if detection bandwidth and spatial averaging were taken into account.
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Physical mechanisms of the therapeutic effect of ultrasound (a review)
Michael R. Bailey, Vera A. Khokhlova, Oleg A. Sapozhnikov et al. · Acoustical Physics · 2003 · 450 citations
High-intensity focused ultrasound for the treatment of liver tumours
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Michael Canney, Michael R. Bailey, Lawrence A. Crum et al. · The Journal of the Acoustical Society of America · 2008 · 290 citations · Full text
Wayne Kreider, Petr V. Yuldashev, Oleg A. Sapozhnikov et al. · IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control · 2013 · 138 citations · Full text