Perfusion rates of brain, intestine and heart under conditions of total body perfusion

Abstract

The perfusion rates of the brain, intestine and heart ventricle were studied under conditions of total body perfusion. The perfusion rates were estimated by using antipyrine and D 2 O as reference substances. Local flow was determined from arterial curves and tissue analysis. When the total body perfusion rate was varied between 20 and 80 cc/kg/min., it was found at each rate that the perfusion rate of these organs was over three times that of the body as a whole. At the lowest flows these three organs were favored even more. Tables of perfusion rates at various sites in the brain and intestine are given. Pressure-flow curves for the brain, intestine and heart are given.