Phenyliodine(III) Diacetate Mediated Oxidative Cyclization of 1-Alkenoyl-1-carbamoyl Cycloalkanes: Access to Spiro-Fused Dihydrofuran-3(2<i>H</i>)-ones

Abstract

Facile and efficient synthesis of spiro-fused dihydrofuran-3(2H)-ones was developed via phenyliodine(III) diacetate (PIDA) mediated oxidative cyclization of 1-alkenoyl-1-carbamoyl cycloalkanes under very mild conditions.