Physico-chemical characterization of collagen scaffolds for tissue engineering

Abstract

The objective was to research the physical and chemical properties of collagen scaffolds (CS) obtained from bone matrix Nukbone® subject toa demineralization process using hydrochloric acid. The CS samples were characterized by optical and scanning electron microscopy, elementalchemical analysis, X-ray diffraction, spectroscopy Infrared, thermal analysis, differential scanning calorimetry and nitrogen adsorption. Themicroanalysis were used to set the macro- and microstructures of CS. They showed that the CS retained the morphology of Nukbone® withinterconnected pores and their size between 100 and 500