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Loss of P53 Function Activates JAK2–STAT3 Signaling to Promote Pancreatic Tumor Growth, Stroma Modification, and Gemcitabine Resistance in Mice and Is Associated With Patient Survival

Stroma ModificationTumor BiologySignaling PathwayPancreatic CancerCell RegulationMedicineGemcitabine ResistanceCancer Cell BiologyPatient SurvivalTumor SuppressorRadiation OncologyCancer BiologyCell BiologyCell SignalingTumor MicroenvironmentCancer ResearchJak-stat Signaling PathwayMolecular Signaling