Physics in Medicine and Biology · 2016 · 11 citations · 33 references
EngineeringNuclear EngineeringNuclear MedicineRadiation DetectionRadiation DosimetryRadiation MeasurementDetector TechnologyNuclear Medicine PhysicsProton DosimetryProton TherapyRadiation DetectorsScintillation DetectorsCommissioning Of Small FieldsDetector Spatial ResolutionGas Electron MultipliersHigh-resolution DosimetryProton Therapy DosimetryScintillationScintillation DosimetrySpatial Resolution In Dosimetry
Accurate, high-spatial resolution dosimetry in proton therapy is a time consuming task, and may be challenging in the case of small fields, due to the lack of adequate instrumentation. The purpose of this work is to develop a novel dose imaging detector with high spatial resolution and tissue equivalent response to dose in the Bragg peak, suitable for beam commissioning and quality assurance measurements. A scintillation gas electron multiplier (GEM) detector based on a double GEM amplification structure with optical readout was filled with a He/CF4 gas mixture and evaluated in pristine and modulated proton beams of several penetration ranges. The detector's performance was characterized in terms of linearity in dose rate, spatial resolution, short- and long-term stability and tissue-equivalence of response at different energies. Depth-dose profiles measured with the GEM detector in the 115-205 MeV energy range were compared with the profiles measured under similar conditions using the PinPoint 3D small-volume ion chamber. The GEM detector filled with a He-based mixture has a nearly tissue equivalent response in the proton beam and may become an attractive and efficient tool for high-resolution 2D and 3D dose imaging in proton dosimetry, and especially in small-field applications.
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PROTON RANGE ENERGY TABLES, 1-KEV - 10-GEV. 1.
J Janni · Atomic Data and Nuclear Data Tables · 1982 · 404 citations