A Slowing Down of Circadian Rhythms by Lithium Ions

Abstract

Abstract Unter the permanent influence of lithium ions the circadian rhythm of movement of Kalanchoe petals is effectively lengthened but a pulse administered up to 12 hours has no influence. Lithium ions could also be demonstrated to similarly slow down the circadian activity rhythm of a small mammal (Meriones crassus). It is hypothesized that the therapeutic effect of lithium salts in endogenous depressions in human beings may result also from its acting on the human circadian system