Macromolecular prodrugs

Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents-drug-polymer conjugates. Cancer Research Campaign Phase I/II Committee.

P. Vasey, Stan B. Kaye, Rachel Morrison et al. · PubMed · 1999 · 691 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Coupling of the antiviral agent zidovudine to polyaspartamide and in vitro drug release studies

Gaetano Giammona, Gennara Cavallaro, Giacomo Fontana et al. · Journal of Controlled Release · 1998 · 73 citations

Medicine, Infectious Diseases, Pharmacology +12

Chemical stability and bioavailability of acyclovir coupled to α,β-poly(N-2-hydroxyethyl)-dl-aspartamide

Gaetano Giammona, Giovanni Puglisi, Gennara Cavallaro et al. · Journal of Controlled Release · 1995 · 72 citations

Pharmacy, Pharmacokinetics, Pharmacology +9

Properties and reactivity of polysuccinimide

Jirina Vlasak, František Rypáček, J. Drobník et al. · Journal of Polymer Science Polymer Symposia · 1979 · 68 citations

Natural Sciences, Biochemistry, Chemistry +8

Reactions with 1-benzotriazolecarboxylic acid chloride. VIII. Synthesis of N -hydroxyisocyanate derivatives

Ivan Butula, Milena Jadrijević-Mladar Takač · Hrčak Portal of scientific journals of Croatia (University Computing Centre) · 2000 · 37 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +11