Concepedia

Publication | Open Access

Poly (ADP-Ribose) Polymerase Inhibitor Hypersensitivity in Aggressive Myeloproliferative Neoplasms

DOIFull Paper Access

25

Citations

34

References

2016

Year

Keith W. Pratz, Brian D. Koh, Anand G. Patel, Karen S. Flatten, Weijie Poh, James G. Herman, Robert L. Dilley, Maria I. Harrell, B. Douglas Smith, Judith E. Karp,
Clinical Cancer Research

Abstract

Like other neoplasms with HR defects, MPNs exhibit PARP inhibitor hypersensitivity compared with normal marrow. These results suggest that further preclinical and possibly clinical study of PARP inhibitors in MPNs is warranted. Clin Cancer Res; 22(15); 3894-902. ©2016 AACR.

References

YearCitations

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