Cyproterone acetate <i>vs</i> leuprolide acetate in combination with transdermal oestradiol in transwomen: a comparison of safety and effectiveness

Abstract

Preliminary results from this retrospective observational pilot study suggest that CPA and Leu in combination with TE are equally effective in the suppression of gonadotrophins and testosterone levels over 1 year. Whether the different effects on HDL-cholesterol may lead to long-term different cardiovascular safety profiles remains to be defined.