Tumor necrosis factor-alpha protects synovial cells from nitric oxide induced apoptosis through phosphoinositide 3-kinase Akt signal transduction. - Concepedia

Concepedia

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Tumor necrosis factor-alpha protects synovial cells from nitric oxide induced apoptosis through phosphoinositide 3-kinase Akt signal transduction.

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References

2006

Year

Qingquan Chen, Bruno Casali, Laura Pattacini, Luigi Boiardi, Carlo Salvarani

Abstract

TNF-a has an anti-apoptotic effect in human FLS. Activation of Akt and BAD may have an important role in this process.