Facile Synthesis of 3-<i>N</i>-Alkyl Pyrimidin-2,4-diones from <i>N</i>-Sulfonyloxy Maleimides and Amines

Abstract

Reaction of variously substituted N-trifluoromethanesulfonyloxy maleimides with primary amines in the presence of potassium carbonate in DMF at room temperature results in the formation of 3-N-alkyl pyrimidin-2,4-diones in good yield.