AFRICAN JOURNAL OF BIOTECHNOLOGY · 2012 · 18 citations · 40 references
Open access
Veterinary MedicinePharmacologyToxicologyEnvironmental ToxicologyMechanisms Of ToxicityPesticide ToxicologyInsecticide ToxicityInsecticide ToxicologyMechanisms Of Pesticide ToxicityMolecular Mechanisms Of ToxicityPesticide EcotoxicologyPesticide PoisoningAdverse Health EffectsOrganochlorine NeurotoxicityOrganochlorine PoisoningOxidative Stress AdaptationOxidative Stress In Toxicant ExposureOxidative Stress InjuryOxidative Stress InteractionsPesticide-induced Oxidative Stress
The present paper reviews the mechanism underlying chlorpyrifos and cypermethrin poisoning. It explains the mechanism of action of chlopyrifos and cypermethrin and the role of oxidative stress. It sheds light on the interaction between chlopyrifos and cypermethrin as observed in many cocktails of pesticide combinations today. It also explains the adverse health effects of pesticides and some antioxidants which may ameliorate their effects. Further research aimed at identifying more agents that may ameliorate chlorpyrifos and cypermethrin-induced toxicity should be carried out. Key words : Pesticides, chlorpyrifos, cypermethrin oxidative stress, antioxidant.
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