The Relationship Between Invasive Nontyphoidal<i>Salmonella</i>Disease, Other Bacterial Bloodstream Infections, and Malaria in Sub-Saharan Africa

Abstract

A positive correlation between iNTS disease and malaria endemicity, and the association between Plasmodium parasite positivity and iNTS disease across sub-Saharan Africa, indicates the necessity to consider iNTS as a major cause of febrile illness in malaria-holoendemic areas. Prevention of iNTS disease through iNTS vaccines for areas of high malaria endemicity, targeting high-risk groups for Plasmodium parasitic infection, should be considered.