Thecal cell sensitivity to luteinizing hormone and insulin in polycystic ovarian syndrome

Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome

John E. Nestler, Daniela Jakubowicz · New England Journal of Medicine · 1996 · 750 citations · Full text

Medicine, Biochemistry, Endocrinology +17

Insulin Stimulates Testosterone Biosynthesis by Human Thecal Cells from Women with Polycystic Ovary Syndrome by Activating Its Own Receptor and Using Inositolglycan Mediators as the Signal Transduction System¹

John E. Nestler, Daniela Jakubowicz, Aı́da Falcón de Vargas et al. · The Journal of Clinical Endocrinology & Metabolism · 1998 · 572 citations

Life Sciences, Biochemistry, Endocrinology +15

Evidence for Distinctive and Intrinsic Defects in Insulin Action in Polycystic Ovary Syndrome

Andrea Dunaif, Karen R. Segal, Donna Shelley et al. · Diabetes · 1992 · 517 citations

Medicine, Endocrinology, Gynecology +13

Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries.

Carole Gilling‐Smith, Debbie Willis, R.W. Beard et al. · The Journal of Clinical Endocrinology & Metabolism · 1994 · 413 citations

Medicine, Endocrinology, Gynecology +17

Cellular mechanisms of insulin resistance in polycystic ovarian syndrome.

Theodore P. Ciaraldi, Albert El-Roeiy, Zecharia Madar et al. · The Journal of Clinical Endocrinology & Metabolism · 1992 · 326 citations

Medicine, Endocrinology, Physiology +17