Association of growth differentiation factor 11/8, putative anti-ageing factor, with cardiovascular outcomes and overall mortality in humans: analysis of the Heart and Soul and HUNT3 cohorts

Kristoff Olson, Alexis L. Beatty, Bettina Heidecker, Mathilda Regan, Edward N. Brody, Trudi Foreman, Shintaro Kato, Robert Mehler, Britta Swebilius Singer, Kristian Hveem,

European Heart Journal · 2015 · 118 citations · 19 references

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Abstract

In patients with stable ischaemic heart disease, higher GDF11/8 levels are associated with lower risk of cardiovascular events and death. Our findings suggest that GDF11/8 has similar cardioprotective properties in humans to those demonstrated in mice.

References

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