Flexible Octopus‐Shaped Hydrogel Particles for Specific Cell Capture

Lynna Chen, Harry Z. An, Ramin Haghgooie, Aaron T. Shank, Joseph M. Martel, Mehmet Toner, Patrick S. Doyle

Small · 2016 · 41 citations · 49 references

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Abstract

Multiarm hydrogel microparticles with varying geometry are fabricated to specifically capture cells expressing epithelial cell adhesion molecule. Results show that particle shape influences cell-capture efficiency due to differences in surface area, hydrodynamic effects, and steric constraints. These findings can lead to improved particle design for cell separation and diagnostic applications. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

References

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