Small · 2016 · 41 citations · 49 references
EngineeringBioengineeringBiomedical EngineeringBiomaterialsBiosensorsCell AdhesionCell EncapsulationHydrogel BiomaterialsHydrogelsMicrofluidicsNanomedicineNanoparticle DesignCell-laden HydrogelsHydrodynamic Interaction EffectsHydrogel MaterialsHydrogel MicroparticlesHydrogel-based SystemsParticle ShapeSteric ConstraintsSurface Area
Multiarm hydrogel microparticles with varying geometry are fabricated to specifically capture cells expressing epithelial cell adhesion molecule. Results show that particle shape influences cell-capture efficiency due to differences in surface area, hydrodynamic effects, and steric constraints. These findings can lead to improved particle design for cell separation and diagnostic applications. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Hemodynamic Shear Stress and Its Role in Atherosclerosis
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Isolation of rare circulating tumour cells in cancer patients by microchip technology
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Medicine, Cancer Biology, Oncology +15
Shape effects of filaments versus spherical particles in flow and drug delivery
Yan Geng, Paul Dalhaimer, Shenshen Cai et al. · Nature Nanotechnology · 2007 · 2.5K citations · Full text