Concepedia

Publication | Open Access

Signalling via the osteopontin and high mobility group box-1 axis drives the fibrogenic response to liver injury

DOIFull Paper Access

138

Citations

26

References

2016

Year

Elena Arriazu, Xiaodong Ge, Tungming Leung, Fernando Magdaleno, Aritz Lopategi, Yongke Lu, Naoto Kitamura, Raquel Urtasun, Neil D. Theise, Daniel J. Antoine,
Gut

Abstract

During liver fibrosis, the increase in OPN induces HMGB1, which acts as a downstream alarmin driving collagen-I synthesis in HSCs.

References

YearCitations

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