Full characterization of the integrative and conjugative element carrying the metallo-β-lactamase<i>bla</i>_SPM-1and bicyclomycin<i>bcr1</i>resistance genes found in the pandemic<i>Pseudomonas aeruginosa</i>clone SP/ST277 : Figure 1.

Abstract

The presence of bla SPM-1 in a Tn4371-ICE with intact integration/conjugation modules demonstrated that, besides gene dispersion by clonal expansion of the pandemic SP/ST277 lineage, bla SPM-1 may be spread through ICE conjugation.