Distribution of Messenger RNAs for Aldehyde Dehydrogenase 1, Aldehyde Dehydrogenase 2, and Aldehyde Dehydrogenase 5 in Human Tissues

Abstract

The results are in general agreement with the distribution of enzymes studied in a limited number of tissues in the past, with the exception that the ALDH1 activity reported to exist in heart and brain may, in fact, be ALDH5. The only mRNA detected in placenta was that for ALDH5. This study extends the knowledge of the expression of these enzymes to several tissues not previously studied and establishes the tissue distribution of the new enzyme ALDH5.