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Hemodynamic Effects of Ethanol in Patients with Cardiac Disease
16
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1972
Year
HypertensionHeart FailurePeripheral ResistanceCardiovascular PharmacologyCardiovascular FunctionCardiovascular ToxicityAlcohol MisusePulmonary Artery PressureHemodynamic EffectsCardiologyAtherosclerosisHeart RateAlcohol AbuseAlcohol DependenceCardiovascular DiseasePhysiologyCardiovascular PharmacodynamicsMedicineAnesthesiology
After 30 minutes, 90 cc of whisky containing 43% alcohol produced no significant changes in heart rate, systemic arterial pressure or pulmonary artery pressure in 15 nonalcoholics with cardiac disorders. Left ventricular end-diastolic pressure rose significantly. The stroke index remained the same or fell while arterial pressure did not change, consequently peripheral resistance rose, contrary to the view that alcohol is a peripheral vasodilator.