Investigation of the Initial Crystallization Stage in Lysozyme Solutions by Small-Angle X-ray Scattering

M. V. Kovalchuk, Yulia A. Dyakova, Andrey Gruzinov, G. S. Peters, Yu. V. Pisarevsky

Crystal Growth & Design · 2016 · 66 citations · 27 references

Concepts

Abstract

From the base structure of tetragonal lysozyme crystals, the octamer cluster was selected as the possible element of crystal growth. The proposed model was verified by small-angle X-ray scattering (SAXS) measurements of lysozyme solutions. The results showed a noticeable presence of lysozyme dimers and octamers under crystallization conditions and the total absence of oligomers under conditions where crystal growth was impossible.

References

27