HOTAIR in Relation to Epithelial-Mesenchymal Transition and Cancer Stem Cells in Molecular Subtypes of Endometrial Cancer

Abstract

Our data do not confirm the role of HOTAIR in EMT-mediated CSC formation in EC. Neither does the diversity of EC molecular subtypes influence these processes. But HOTAIR expression could serve as an independent prognostic factor in EC. The clinical importance of the above discoveries requires further studies.