The Aberrant Expression of Stimulatory and Inhibitory Killer Immunoglobulin-Like Receptors in NK- and NKT-Cells Contributes to Lupus

Abstract

We found that SLE patients represent aberrant expression of stimulatory and inhibitory KIRs in NK- and NKT-cells. Consequently, these different expression levels of KIRs may contribute to the abnormal function of these cells, which lead to the risk of SLE.