Hypothalamic neurogenesis persists in the aging brain and is controlled by energy-sensing IGF-I pathway

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

Linda Madisen, Theresa A. Zwingman, Susan M. Sunkin et al. · Nature Neuroscience · 2009 · 7.4K citations · Full text

Life Sciences, Neurobiology, Neuroscience +10

A C. elegans mutant that lives twice as long as wild type

Cynthia Kenyon, Jean Chang, Erin Gensch et al. · Nature · 1993 · 3.4K citations

Life Sciences, Biology, Genetics +6

IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Martin Holzenberger, Joëlle Dupont, Bertrand Ducos et al. · Nature · 2002 · 2.1K citations · Full text

Education, Genetics, Molecular Genetics +12

Extension of Life-Span by Loss of CHICO, a <i>Drosophila</i> Insulin Receptor Substrate Protein

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Education, Biology, Genetics +17

Noggin Antagonizes BMP Signaling to Create a Niche for Adult Neurogenesis

Daniel A. Lim, Anthony D. Tramontin, José Trevejo et al. · Neuron · 2000 · 1.1K citations · Full text

Medicine, Developmental Biology, Neurobiology +13