Concepedia

Publication | Closed Access

Effects of Uric Acid on the NO Production of HUVECs and its Restoration by Urate Lowering Agents

DOI

69

Citations

0

References

2016

Year

Mutsuo Mishima, Toshihiro Hamada, Nani Maharani, Naho Ikeda, Takeshi Onohara, Tomomi Notsu, Haruaki Ninomiya, Satoshi Miyazaki, Einosuke Mizuta, Shinobu Sugihara,
Drug Research

Abstract

Urate reduced NO production by impaired phosphorylation of eNOS in HUVEC via activation of UATs, which could be normalized by urate lowering agents.