Addison's disease with polyglandular autoimmunity carries a more than 2·5‐fold risk for adrenal crises: German Health insurance data 2010–2013

Abstract

Applying a SHI database comprising more than 9 million individuals, we identified robust data about the risk of AC in different groups of patients with AI. Our data confirm and extend the clinical observation that patients with APS are at highest risk for AC. Approximately 1 of 8 patients with primary AI and type 1 diabetes suffers from an AC each year. Specific targeting of efforts aiming at the prevention of AC is necessary.