In-vitro Anti-arthritic Activity of Manilkara zapota Linn

Abstract

The present study is aimed to evaluate the leaf extract of Manilkara zapota for acclaimed anti-arthritic activity using in-vitro inhibition of protein denaturation model. Acetyl salicylic acid was used as a standard drug. Results revealed that the ethanolic extract of Manilkara zapota at two different concentrations (100mcg/ml and 250mcg/ml) possessed significant anti-arthritic activity as compared to standard used drug acetyl salicylic acid. The plant extract showed dose dependent activity.