Clinicopathological predictive factors in the early remission of corticotroph pituitary macroadenomas in a tertiary referral centre

Abstract

Corticotroph macroadenomas differ from the more common microadenomas not only in terms of hormonal and imaging characteristics but also in terms of immunohistochemical and ultrastructural features and proliferation markers. The early effectiveness of surgery depends primarily on tumour volume and invasiveness.