Sjogren's Syndrome treated with ACTH

Abstract

IN this paper we report observations on the treatment with ACTH of six female patients suffering from Sj6gren's syndrome. Each case was investig- ated on two occasions, an initial period of observation preceding the second admission for treatment. Five of the six patients underwent parotid biopsy, typical histological changes being seen in all. The methods used to assess improvement during therapy are described below.