The Medical Journal of Australia · 1979 · 19 citations · 13 references
PharmacyCardiologyPharmacologyCardiovascular PharmacotherapyPharmaceutical ToxicologyPoisoning ManagementAntiarrhythmic TherapyArrhythmia PharmacotherapyCardiac ArrhythmiasCardiotoxicity ManagementCardiovascular Drug SafetyDrug Overdose ManagementAcute Cardiac ToxicityAntiarrhythmic Drug ToxicityCardiotoxic Poisoning AssessmentCardiotoxicityCardiovascular Complications Of OverdoseCardiovascular Drug ToxicityCardiovascular Toxicity ManagementDrug-induced Arrhythmias
A case of fatal cardiotoxicity after a deliberate ingestion of 5000 mg thioridazine (Melleril) is reported. The serum thioridazine level is documented for the first time at the time of arrhythmia. Correct treatment of similar cases should often include insertion of a transvenous pacing wire, as the arrhythmias are generally resistant to drug therapy.
13
The Pharmacological Basis of Therapeutics
Justus F. Mueller, Louis S. Goodman, Alfred G. Gilman · Journal of Parasitology · 1976 · 855 citations
Sudden Death During Treatment With Phenothiazine Derivatives
Leo E. Hollister · JAMA · 1965 · 166 citations
Medicine, Pharmacology, Psychiatry +10