Publication | Closed Access
Chiral Phosphoric Acid Catalyzed Asymmetric Synthesis of 2-Substituted 2,3-Dihydro-4-quinolones by a Protecting-Group-Free Approach
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Citations
33
References
2015
Year
2-Substituted 2,3-Dihydro-4-quinolonesEngineeringProtecting-group-free ApproachOrganic ChemistryStereoselective SynthesisChemistryChiral Phosphoric AcidChiral 2-Substituted 2,3-Dihydro-4-quinolonesAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringGood Yields
Chiral 2-substituted 2,3-dihydro-4-quinolones were synthesized based on the chiral phosphoric acid catalyzed intramolecular aza-Michael addition reaction using N-unprotected 2-aminophenyl vinyl ketones as substrates in good yields with high enantioselectivities.
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