Epoxy and aziridinyl enolsilanes in diastereoselective inter- and intramolecular Friedel–Crafts alkylations

Abstract

Diastereoselective Friedel–Crafts reactions of optically pure epoxy enolsilanes afford enantiomerically-enriched β-hydroxy-α-arylketones. Aziridinyl enolsilanes react in an analogous manner.