Visible-Light-Mediated 1,7-Enyne Bicyclizations for Synthesis of Cyclopenta[<i>c</i>]quinolines and Benzo[<i>j</i>]phenanthridines

Abstract

A photocatalytic process for 1,7-enyne bicyclizations with α-bromo diethyl malonate has been established via synergistic domino bicyclizations. This protocol provides an efficient and practical method for the synthesis of various cyclopenta[c]quinolines and benzo[j]phenanthridines under operational simplicity and mild reaction conditions.