Short-chain C2 ceramide induces heme oxygenase-1 expression by upregulating AMPK and MAPK signaling pathways in rat primary astrocytes

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

Marcelo R. Vargas, Delinda A. Johnson, Daniel W. Sirkis et al. · Journal of Neuroscience · 2008 · 475 citations · Full text

Medicine, Neurobiology, Neuroscience +17

AMP-activated Protein Kinase Is Required for the Lipid-lowering Effect of Metformin in Insulin-resistant Human HepG2 Cells

Mengwei Zang, Adriana Zuccollo, Xiuyun Hou et al. · Journal of Biological Chemistry · 2004 · 454 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

The Crosstalk Between Nrf2 and AMPK Signal Pathways Is Important for the Anti-Inflammatory Effect of Berberine in LPS-Stimulated Macrophages and Endotoxin-Shocked Mice

Chunfen Mo, Ling Wang, Jie Zhang et al. · Antioxidants and Redox Signaling · 2013 · 438 citations · Full text

Life Sciences, Biochemistry, Immunology +17

Activated AMPK boosts the Nrf2/HO-1 signaling axis—A role for the unfolded protein response

Kristin Zimmermann, Johannes Baldinger, Barbara Mayerhofer et al. · Free Radical Biology and Medicine · 2015 · 254 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Resveratrol improves oxidative stress and prevents the progression of periodontitis via the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense pathways in a rat periodontitis model

Naofumi Tamaki, Rita Cristina Orihuela-Campos, Yuji Inagaki et al. · Free Radical Biology and Medicine · 2014 · 207 citations

Dentistry, Oral Biology, Periodontics +13