Human Reproduction · 1993 · 18 citations · 0 references
Veterinary MedicineGynecologyObstetricsEmbryologyIn Vitro FertilizationReproductive MedicineEmbryo EvaluationPost-thaw Embryo TransferPregnancyCryopreservation Effects On BlastocystsDizygotic TwinsMonozygotic Twin ProductionMonozygotic TwinsReproductive Outcome After Embryo ThawingTwin Pregnancy ManagementZygote Intrafallopian Transfer
Assisted hatching techniques enhance the success rate of implantation of in-vitro fertilized human embryos. We report here the successful transfer of a frozen-thawed human blastocyst on which we applied a non-invasive zona rubbing technique (reduction of the thickness of the zona pellucida by gentle rubbing with a microneedle). The implantation in the uterus led to the delivery of healthy monozygotic twins.