Early life stress increases stress vulnerability through BDNF gene epigenetic changes in the rat hippocampus

Behavioural despair in rats: A new model sensitive to antidepressant treatments

Roger D. Porsolt, Guy Anton, N. Blavet et al. · European Journal of Pharmacology · 1978 · 3.1K citations

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Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Peter Lloyd Jones, Gert Jan C. Veenstra, Paul A. Wade et al. · Nature Genetics · 1998 · 2.7K citations

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Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

Masashi Nibuya, Shigeru Morinobu, R. S. Duman · Journal of Neuroscience · 1995 · 2.1K citations · Full text

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MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

Maria H. Chahrour, Sung Yun Jung, Chad A. Shaw et al. · Science · 2008 · 1.8K citations

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Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action

Nadia M. Tsankova, Olivier Berton, William Renthal et al. · Nature Neuroscience · 2006 · 1.8K citations

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