PubMed · 2008 · 18 citations · 24 references
Perioperative MedicineDowns Syndrome ConstitutesSurgeryCongenital DisordersCraniofacial AnomaliesPediatric SurgeryCommon Chromosomal DisorderPediatric SpineRegional AnesthesiaDown SyndromeSpinal Cord InjuryAnesthesia PracticeDevelopmental AnomalyDowns SyndromePediatricsCraniofacial SurgeryAnesthesiaMedicineCraniofacial DisorderAnesthesiology
Downs syndrome constitutes to be the most common chromosomal disorder. Patients with Downs's syndrome are posted for several surgeries including dental procedures and even for facial reconstruction. They are associated with several congenital anomalies in different organ system. There is also increased incidence of atlanto axial instability and risk of spinal cord injury. These children are susceptible to infection and they are also considered to be hypersensitive to the effect or atropine. These all factors modify the anesthetic implication and also anesthetic management in these cases. We have highlighted all these factors and reviewed the anesthetic implication of these child posted for several procedures under anesthesia.
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Down's syndrome: an atheroma-free model?
Jamie Murdoch, J C Rodger, Srinivas Rao et al. · BMJ · 1977 · 216 citations · Full text
Airway anomalies in children with Down syndrome: endoscopic findings
P. Bertrand, Héctor Navarro, Solange Caussade et al. · Pediatric Pulmonology · 2003 · 188 citations