Chicken embryonic stem cells and primordial germ cells display different heterochromatic histone marks than their mammalian counterparts

Abstract

Chicken ESCs and PGCs differ from their mammalian counterparts with respect to H3K27 methylation. High enrichment of H3K27me3 at PCH is specific to pluripotent cells in chicken. Our results demonstrate that the dynamics in chromatin constitution described during mouse development is not universal to all vertebrate species.