Phase II and pharmacologic study of topotecan administered as a 21-day continuous infusion to patients with colorectal cancer.

G.J. Creemers, C J Gerrits, Jan H.M. Schellens, André Planting, M E van der Burg, V M van Beurden, M de Boer-Dennert, Miranda Harteveld, Walter J. Loos, I Hudson,

Journal of Clinical Oncology · 1996 · 65 citations · 0 references

Abstract

Topotecan administered as a 21-day continuous infusion exerts minor activity as single-agent therapy in patients with metastatic colorectal cancer.