PERMANENT NEONATAL DIABETES MELLITUS DUE TO A C96Y HETEROZYGOUS MUTATION IN THE INSULIN GENE

A mutation in the insulin 2 gene induces diabetes with severe pancreatic β-cell dysfunction in the Mody mouse

Jie Wang, Toshiyuki Takeuchi, Shigeyasu Tanaka et al. · Journal of Clinical Investigation · 1999 · 570 citations · Full text

Medicine, Endocrinology, Molecular Biology +17

Insulin gene mutations as a cause of permanent neonatal diabetes

Julie Støy, Emma L. Edghill, Sarah E. Flanagan et al. · Proceedings of the National Academy of Sciences · 2007 · 557 citations · Full text

Medicine, Endocrinology, Genetics +16

Insulin Mutation Screening in 1,044 Patients With Diabetes

Emma L. Edghill, Sarah E. Flanagan, Ann‐Marie Patch et al. · Diabetes · 2007 · 400 citations · Full text

Medicine, Genetics, Molecular Genetics +16

Heterozygous Missense Mutations in the Insulin Gene Are Linked to Permanent Diabetes Appearing in the Neonatal Period or in Early Infancy

Michel Polak, Aurélie Dechaume, Hélène Cavé et al. · Diabetes · 2008 · 134 citations · Full text

Medicine, Endocrinology, Genetics +17