PubMed · 1985 · 36 citations · 14 references
MedicineGeneticsOphthalmologyHuman GeneticsOcular DiseaseOcular GeneticsAge-related Macular DegenerationMacular DegenerationMacular DiseaseMacular DisordersRetinal DegenerationAge-related Macular Degeneration HeritabilityDizygotic TwinsHereditary Ocular DiseaseInherited Ocular DiseaseMendelian Risk FactorsMonozygotic TwinsNeovascularizationPigmentation
This is the first report, to our knowledge, of proliferative macular degeneration developing in the same eye of identical twins. The concept of a familial predisposition in age related macular degeneration is consistent with other known risk factors including race, iris pigmentation, hyperopia and macular drusen which are known to be genetically determined. Monozygotic twins provide ophthalmology with an excellent opportunity to study the hereditary aspects of ocular disease.
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SENILE MACULAR DEGENERATION: A CASE-CONTROL STUDY
Leslie Hyman, Abraham M. Lilienfeld, Frederick L. Ferris et al. · American Journal of Epidemiology · 1983 · 592 citations
Retinal degeneration in monkeys induced by deficiencies of vitamin E or A.
K. C. Hayes · PubMed · 1974 · 173 citations